Retatrutide Dosage Calculator

Enter the amount in your Retatrutide vial, the volume it is in, and the dose you want expressed in syringe units. This page computes the arithmetic of those values — concentration, the volume to draw, insulin-syringe units, and doses per vial. It is not a dosing recommendation.

40syringe units (U-100)
Concentration
5 mg/mL
Draw volume
0.4 mL
Doses per vial
5
0102030405060708090100

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The values above are pre-filled as a worked example so the page loads with numbers to read. They are not a recommended vial size, diluent volume, or dose. Change any field to compute your own.

Retatrutide at a glance

Also known as
LY3437943
Compound class
Incretin receptor agonist (peptide)
Supplied as
Lyophilized (freeze-dried) powder — dissolved in a diluent before any volume can be drawn
Vial strengths
5 mg lyophilized vial — commonly supplied · 10 mg lyophilized vial — commonly supplied · 15 mg lyophilized vial — commonly supplied · 20 mg lyophilized vial — commonly supplied · 30 mg lyophilized vial — commonly supplied
Regulatory status
This compound is investigational: it is under study in clinical trials and there is no FDA-approved product containing it in any form. Because no product is approved, no approved labeling defines a vial strength, a diluent, or a concentration for it.

What Retatrutide is

Retatrutide (development code LY3437943) is a synthetic peptide that acts as an agonist at three receptors at once: the GIP receptor, the GLP-1 receptor, and the glucagon receptor.

It is investigational — it has been studied in Phase 1, Phase 2 and Phase 3 clinical trials, and no FDA-approved retatrutide product exists, so there is no approved labeling that states a vial strength, a diluent, or a concentration.

Material supplied as a lyophilized (freeze-dried) powder has to be dissolved before any volume can be drawn, and the concentration that results is set entirely by the mass in the vial and the volume of diluent added to it.

This page's calculator computes that concentration, the volume to draw, and the equivalent insulin-syringe units from the numbers you enter.

Load a vial strength into the calculator

Each link re-runs the calculator above with that strength's numbers already entered.

Rows marked FDA-approved are strengths stated in approved labeling. Rows marked commonly supplied are vial sizes that compounded and research presentations are commonly supplied in; no approved labeling defines those, and what a given vial contains is only what is printed on that vial.

Retatrutide calculator questions

How many units is a 2 mg dose of Retatrutide?

With the example values on this page — 10 mg in 2 mL of bacteriostatic water — the vial works out to 5 mg/mL, so a 2 mg dose is 0.4 mL, which reads as 40 units on a U-100 insulin syringe. Change any field in the calculator above and the computed units change with it.

What does a 10 mg vial of Retatrutide come out to with different amounts of bacteriostatic water?

Concentration is the mass in the vial divided by the volume it is in, so changing only the volume changes every downstream number: 1 mL computes to 10 mg/mL, making a 2 mg dose 0.2 mL (20 units); 2 mL computes to 5 mg/mL, making a 2 mg dose 0.4 mL (40 units); 4 mL computes to 2.5 mg/mL, making a 2 mg dose 0.8 mL (80 units). Each figure is arithmetic on the two values stated, not a statement that any of those volumes is the one to use.

How many 2 mg doses are in a 10 mg vial of Retatrutide?

Dividing 10 mg by 2 mg computes to 5 full doses. Only whole doses are counted — any remainder smaller than a full dose is left out of that figure. Different vial contents or a different dose produce a different count; enter yours in the calculator above.

What concentration is 10 mg of Retatrutide in 2 mL?

10 mg in 2 mL computes to 5 mg/mL. From that concentration, the volume holding a 2 mg dose is 0.4 mL, or 40 units on a U-100 syringe. This page reports that division; it does not evaluate the numbers you put into it.

How much bacteriostatic water do I add to a vial of Retatrutide?

That volume is an input to this calculator, not an output of it — this page does not pick a volume for you and nothing here says which one to use. What it can tell you is what each choice computes to: 10 mg with 1 mL works out to 10 mg/mL, and the same 10 mg with 4 mL works out to 2.5 mg/mL. The mass in the vial never changes; only the concentration and the volume you would draw do.