HCG Dosage Calculator
Enter the amount in your HCG vial, the volume it is in, and the dose you want expressed in syringe units. This page computes the arithmetic of those values — concentration, the volume to draw, insulin-syringe units, and doses per vial. It is not a dosing recommendation.
- Concentration
- 1,000 IU/mL
- Draw volume
- 0.5 mL
- Doses per vial
- 20
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The values above are pre-filled as a worked example so the page loads with numbers to read. They are not a recommended vial size, diluent volume, or dose. Change any field to compute your own.
HCG at a glance
- Also known as
- human chorionic gonadotropin · chorionic gonadotropin for injection, USP · Pregnyl · Novarel
- Compound class
- Glycoprotein hormone
- Supplied as
- Lyophilized (freeze-dried) powder — dissolved in a diluent before any volume can be drawn
- Vial strengths
- 5,000 USP Units per vial — FDA-approved · 10,000 USP Units per vial — FDA-approved
- Regulatory status
- FDA-approved prescription products containing this ingredient are marketed in the United States, and they are supplied as a lyophilized (freeze-dried) powder that is reconstituted with a diluent before use — the same form this calculator models. Approved labeling for those products is published through the FDA and DailyMed.
What HCG is
Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by the human placenta; the FDA-approved injectable products are supplied as a sterile lyophilized powder in multiple-dose vials of 5,000 or 10,000 USP Units, packaged with a vial of Bacteriostatic Water for Injection as the diluent.
hCG is measured in USP Units — used interchangeably with International Units (IU) — rather than in milligrams, so its concentration works out as units per mL: approved labeling shows a 10,000-unit vial reconstituted with 1 mL of diluent giving 10,000 units/mL, and the same vial reconstituted with 10 mL giving 1,000 units/mL.
Recombinant products such as choriogonadotropin alfa are labeled by mass in micrograms instead, so a microgram figure and a unit figure are not interchangeable between products.
This page's calculator works in whichever unit you enter: give it the vial's unit content and the diluent volume and it computes units per mL, the volume to draw, and the equivalent insulin-syringe units.
Load a vial strength into the calculator
Each link re-runs the calculator above with that strength's numbers already entered.
Rows marked FDA-approved are strengths stated in approved labeling. Rows marked commonly supplied are vial sizes that compounded and research presentations are commonly supplied in; no approved labeling defines those, and what a given vial contains is only what is printed on that vial.
HCG calculator questions
How many units is a 500 IU dose of HCG?
With the example values on this page — 10,000 IU in 10 mL of bacteriostatic water — the vial works out to 1,000 IU/mL, so a 500 IU dose is 0.5 mL, which reads as 50 units on a U-100 insulin syringe. Change any field in the calculator above and the computed units change with it.
What does a 10,000 IU vial of HCG come out to with different amounts of bacteriostatic water?
Concentration is the mass in the vial divided by the volume it is in, so changing only the volume changes every downstream number: 5 mL computes to 2,000 IU/mL, making a 500 IU dose 0.25 mL (25 units); 10 mL computes to 1,000 IU/mL, making a 500 IU dose 0.5 mL (50 units); 20 mL computes to 500 IU/mL, making a 500 IU dose 1 mL (100 units). Each figure is arithmetic on the two values stated, not a statement that any of those volumes is the one to use.
How many 500 IU doses are in a 10,000 IU vial of HCG?
Dividing 10,000 IU by 500 IU computes to 20 full doses. Only whole doses are counted — any remainder smaller than a full dose is left out of that figure. Different vial contents or a different dose produce a different count; enter yours in the calculator above.
What concentration is 10,000 IU of HCG in 10 mL?
10,000 IU in 10 mL computes to 1,000 IU/mL. From that concentration, the volume holding a 500 IU dose is 0.5 mL, or 50 units on a U-100 syringe. This page reports that division; it does not evaluate the numbers you put into it.
How much bacteriostatic water do I add to a vial of HCG?
That volume is an input to this calculator, not an output of it — this page does not pick a volume for you and nothing here says which one to use. What it can tell you is what each choice computes to: 10,000 IU with 5 mL works out to 2,000 IU/mL, and the same 10,000 IU with 20 mL works out to 500 IU/mL. The mass in the vial never changes; only the concentration and the volume you would draw do.